For a collaborative drug therapy management protocol to be valid, the medical doctor must be:

A collaborative drug therapy management protocol is a formal agreement between a physician and a pharmacist that allows the pharmacist to manage a patient's drug therapy based on the established guidelines. For this collaboration to be valid and legally recognized, it is essential that the physician and pharmacist are part of the same medical facility or healthcare system. This ensures continuity of care, communication, and the alignment of treatment objectives between the healthcare providers involved in the patient's care.

When both professionals are employed within the same facility, it facilitates easier access to patient records, better integration of care plans, and a streamlined approach to monitoring the patient's response to therapy. Such proximity allows for immediate collaboration on patient care issues and fosters a team-based approach which ultimately benefits the patient.

In contrast, the other options do not fulfill the requirements typically needed for a valid collaborative protocol. For instance, a physician being employed in any medical facility does not establish the necessary direct collaboration with the pharmacist. Similarly, familial relationships or outsourcing from another facility would not provide the required professional integration. Therefore, being employed at the same facility ensures that the roles and responsibilities in patient management are clearly defined and adhered to.