What rule applies to filling a prescription that includes both prescription and non-prescription medications?

In the context of prescriptions that involve both prescription and non-prescription medications, the important rule is that a prescription must only contain drugs that are authorized by a licensed prescriber. Non-prescription medications, also known as over-the-counter (OTC) medications, do not require a prescription in order to be dispensed.

The main reason for this restriction is that prescriptions are legally binding documents that signify a prescriber's authority and responsibility regarding the patient’s care. Combining prescription and non-prescription medications on the same prescription blank can lead to confusion regarding the prescriber's intentions and potentially compromise patient safety.

While there might be circumstances where a prescriber can recommend OTC medications to a patient, they cannot issue a formal prescription for them, and therefore the two types of medications should not be intertwined in the same prescription order. This strict delineation helps maintain clarity and ensures that all medications are dispensed according to proper medical and legal protocols.

The other answers might suggest varying degrees of permissibility but do not take into account the legal framework governing prescriptions, which prioritizes clarity and responsible prescribing practices.